Pralsetinib Shows Robust Activity in Patients with RET-Altered Medullary Thyroid Cancer
Pralsetinib had activity across all RET alterations and regardless of whether the RET mutation was somatic or germline
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Pralsetinib had activity across all RET alterations and regardless of whether the RET mutation was somatic or germline
Sotorasib was active in patients with KRAS p.G12C mutation
Findings from the EPIC-OPC Study
During long interval studied lung cancer remained the primary tumour source in patients newly diagnosed with brain metastasis
Abemaciclib treatment induces changes in the expression of several cell cycle biomarkers
Tumour infiltrating lymphocyte levels may inform treatment decisions in women younger than 40 years with triple negative breast cancer
TERT promoter mutation may not be linked to MGMT promoter methylation-mediated sensitivity to temozolomide in IDH-wildtype glioblastoma
Nivolumab plus cabozantinib as first-line treatment for advanced clear cell renal cell carcinoma was consistently superior to sunitinib across all subgroups studied
Findings from the PRINCEPS study
CheckMate 238 results at 4-years consistently favour nivolumab across all parameters evaluated
Final overall survival analysis of the nextMONARCH study
Relapse-free interval rates in TOSCA study were poorer in elderly compared with younger patients
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