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It is intended for the treatment of recurrent or advanced dMMR/MSI-H endometrial cancer that has progressed on or following prior treatment with a platinum-containing regimen
A need for immediate restoration of breast cancer screening at full capacity
After 9.1 years of follow-up, a trend toward better long-term imatinib failure-free survival in imatinib treated patients was observed in high-risk subgroup
Approval concerns the treatment of patients with tumours without EGFR, ALK or ROS1 aberrations
Tisagenlecleucel outcomes in relapsed or refractory DLBCL and follicular lymphoma
Long-term follow-up due to risk of cancer
Real-world findings
Cardiac safety is confirmed with longer follow-up after adjuvant dual anti-HER2 treatment for node-positive, HER2-positive early breast cancer
It should be considered as an early surrogate endpoint for clinical trials
They received a positive opinion for the treatment of carcinoma of the colon or rectum, breast cancer, NSCLC, RCC, epithelial ovarian cancer, and carcinoma of the cervix
Evidence for efficacy is based on the results from the Study 1620
During treatment with umbralisib, prophylaxis is recommended for Pneumocystis jirovecii pneumonia and to consider prophylactic antivirals to prevent CMV infection, including CMV reactivation
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