Analysis of the Gut Microbiome Provides Clues to Survival Following Nivolumab Therapy for Advanced Gastric Cancer
Findings from the observational/translational DELIVER study
Oncology News
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EMA Recommends Granting a Conditional Marketing Authorisation for Tafasitamab
It is intended for the treatment of relapsed or refractory diffuse large B‑cell lymphoma not eligible for autologous stem-cell transplant
Adding Avelumab to Preoperative Chemoradiotherapy Provides Promising Anti-Tumour Activity in Locally Advanced Rectal Cancer
Findings from the AVANA study
Expression of AR-regulated Genes in CTCs Is Prognostic for Survival and Radiographic Progression in Metastatic Prostate Cancer
Transcriptional profile detectable in circulating tumour cells could serve as an independent prognostic marker beyond androgen receptor splice variant 7
Trastuzumab Deruxtecan Demonstrates Efficacy in HER2-positive and HER2-low Advanced Gastric Cancer
Findings from a post-hoc exploratory biomarker analysis of DESTINY-Gastric01 study
First-Line Encorafenib, Binimetinib, and Cetuximab Combination Provides Clinical Benefit and Manageable Safety in BRAF V600E–Mutated mCRC
BRAF V600E mutations are identified in 8 to 15% of patients with metastatic colorectal cancer and represent a subtype that carries a poor prognosis
Preoperative ctDNA Levels Are Detectable in the Majority of Patients with Resectable Colorectal Cancer
Findings from molecular subgroup analyses of a prospective observational study GALAXY in CIRCULATE-Japan
ctDNA Analysis is Feasible for Detection of Minimal Residual Disease After Treatment Across a Variety of MMRd Tumour Types
Circulating tumour DNA analysis is a feasible tumour agnostic approach for evaluation of the efficacy of checkpoint blockade in patients at high risk of recurrence
Characterisation of KRAS, Including KRAS G12C, Mutations in Gastrointestinal and Metastatic Colorectal Cancer
Focusing on the KRAS G12C variant
The Investigational PD1 Antibody, Tislelizumab, Shows Promise in Patients With Unresectable Hepatocellular Carcinoma
Tislelizumab showed durable responses and was well tolerated in patients who received previous systemic treatment
EMA Recommends Extension of Therapeutic Indications for Nivolumab
New indication concerns adjuvant treatment of oesophageal or gastro-oesophageal junction cancer with residual disease following prior neoadjuvant chemoradiotherapy
Individualised Nutritional Support Reduce the Risk of Mortality in Cancer Patients with Increased Nutritional Risk
Nutritional support also improved functional and QoL outcomes in a prospective, randomised, controlled EFFORT study