No Survival Benefit for Adding Adjuvant Chemotherapy to Endocrine Therapy in Older Patients with ER-positive/HER2-negative Breast Cancer with High Genomic Grade Index
Final results of the Unicancer ASTER 70s study
Oncology News
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1548 results
Longest Follow-Up of CAR T-Cell Therapy in Mantle Cell Lymphoma Points Out to Long-Term Responses with Manageable Safety in Patients with Relapsed/Refractory Disease
Findings from a pivotal ZUMA-2 study support the investigation of CAR T-cell therapy in earlier lines of treatment
FDA Approves Ivosidenib in Combination with Azacitidine for Newly Diagnosed AML
It is approved for use in the older or patients with comorbidities who have acute myeloid leukaemia with a susceptible IDH1 mutation detected by an FDA-approved test
Substantial Clinical Activity of Teclistamab in Patients with Heavily Pretreated Relapsed or Refractory Multiple Myeloma
Findings from the MajesTEC-1 study
Adagrasib Shows Clinical Efficacy in Patients with Previously Treated KRASG12C-Mutated Advanced NSCLC
Findings from the KRYSTAL-1 study
FDA Approves Nivolumab in Combination with Chemotherapy and Nivolumab in Combination with Ipilimumab for First-Line Treatment of Oesophageal Squamous Cell Carcinoma
Efficacy was evaluated in the CHECKMATE-648 study
High Sensitivity of Mismatch Repair–Deficient Locally Advanced Rectal Cancer to Single-Agent PD1 Blockade
Findings from a prospective phase II study with dostarlimab
Presence of Intratumoural TLSs in Advanced STS as a Potential Predictive Biomarker to Improve Patients’ Selection for Pembrolizumab
Findings from the PEMBROSARC study on presence of tertiary lymphoid structures in patients with advanced soft tissue sarcomas
Treatment with a Hypomethylating Agent Can Activate or Up-regulate Oncogenes
Findings from a combining analysis of MDS patient samples with CRISPR-DiR technology
FDA Approves Azacitidine for Newly Diagnosed Juvenile Myelomonocytic Leukaemia
Evidence for efficacy is based on the results from the AZA-JMML-001 study
Longitudinal Molecular Profiling of CTCs Captures New Insights in mRCC
Findings from the largest circulating tumour cells study in patients with metastatic renal cell carcinoma
R2-ISS: an Improved and Simple Prognostic Staging System Allows Better Stratification of Patients with Intermediate-Risk Newly Diagnosed Multiple Myeloma
Second revision stems on the work of the European Myeloma Network within the European Union–funded HARMONY project