pCR Associated with Improved Survival Outcomes in Patients with Soft Tissue Sarcoma Who Received Neoadjuvant Chemoradiotherapy or Radiotherapy
Findings from ancillary analysis of RTOG 9514 and 0630 studies
Oncology News
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Helicobacter Pylori Infection Modifies the Risk of Gastric Cancer Associated with Germline Pathogenic Variants in Homologous Recombination Genes
Findings from an analysis of two independent study cohorts
Adding Pembrolizumab to Standard Chemotherapy, Followed by Pembrolizumab Maintenance, Results in Longer PFS in Patients with Advanced or Recurrent Endometrial Cancer
Findings from the NRG-GY018 study
Apalutamide Plus ADT Demonstrates a Rapid, Deep, and Durable PSA Decline Associated with Improved Clinical Outcomes in Patients with mCSPC
Findings from a post hoc exploratory analysis of the TITAN study
FDA Grants Accelerated Approval to Retifanlimab-dlwr for Metastatic or Recurrent Locally Advanced Merkel Cell Carcinoma
Evidence for efficacy is based on the results from the PODIUM-201 study
Prognostic Role of Plasmatic BRAF Allele Fraction for Survival in Patients with BRAF V600E-mutated mCRC Treated with BRAF Inhibitor-Based Combination Therapies
Droplet digital PCR detects BRAF allele fraction in ctDNA with high reproducibility and sensitivity, offering an alternative to NGS
FDA Approves Dabrafenib with Trametinib for Paediatric Patients with Low-Grade Glioma with a BRAF V600E Mutation
Evidence for efficacy is based on the results from the Study CDRB436G2201
Neoadjuvant Treatment with Dual Immune Checkpoint Inhibitors Plus Chemotherapy Produces Numerically Higher Major Pathologic Response Rate in Operable NSCLC
Findings from the NEOSTAR phase II platform study
Similarity of Molecular Portraits in Synchronous Bilateral Breast Cancers Could be Influenced by Common Environmental Factors
Findings from a large comprehensive analysis do not support the evidence of a common genetic clonal alteration
Mortality From PSA-Detected Localised Prostate Cancer Remains Very Low Regardless of Whether Patients Received Active Monitoring, Prostatectomy, or Radiotherapy
Findings from the ProtecT study after 15 years of follow-up
Nirogacestat Shows Significant Benefit in Patients with Progressing Desmoid Tumours
Findings from the DeFi study
Persistence of FLT3-ITD or NPM1 Variants in the Blood Associated with Increased Relapse and Worse Survival Among Patients with AML in First Remission Prior to Allogeneic HCT
DNA sequencing findings among patients with acute myeloid leukaemia in first remission prior to allogeneic haematopoietic cell transplant