Asciminib Shows Activity in Heavily Pretreated Patients with CML
It binds to the myristoyl pocket, a previously unexploited feature of ABL1 and ABL2 kinases
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It binds to the myristoyl pocket, a previously unexploited feature of ABL1 and ABL2 kinases
New indication concerns the treatment of metastatic hormone-sensitive prostate cancer in combination with androgen deprivation therapy
ESMO is sad to learn of the death of Professor Pierre Alberto, a wise and thoughtful oncologist whose clinical innovations and educational initiatives had a lasting impact.
Results from the studies with tucatinib, trastuzumab deruxtecan in patients with metastatic breast cancer
CXCR4 antagonist, BL-8040 modifies the tumour microenvironment
TMB is actively being studied as a predictive biomarker for identifying patients who might benefit from immunotherapy but the issue of variability between assays has been raised
Novel combination of sitravatinib and tislelizumab shows manageable safety and promising activity in phase Ib study
Results from analyses of safety, pharmacokinetics and immunogenecity in the CASPIAN trial
Results of the CheckMate 227 - part 2 final analysis
Two studies describe impact of the initiation of steroids early during the course of immune checkpoint inhibition on patient outcome
Nivolumab plus ipilimumab is effective regardless of PD-L1 expression levels in advanced NSCLC
Efficacy of pembrolizumab alone or combined with chemotherapy is solid regardless of KRAS mutations in non-squamous non-small cell lung cancer
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