A Subset of Patients with NSCLC Respond Poorly to the COVID-19 mRNA Vaccines
Very suboptimal vaccine responses generated by subset of patients with non-small cell lung cancer cannot be explained solely by older age and type of vaccine
Oncology News
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FDA Grants Accelerated Approval to Dabrafenib in Combination with Trametinib for Unresectable or Metastatic Solid Tumours with BRAF V600E mutation
Safety and efficacy were evaluated in BRF117019, NCI-MATCH, CTMT212X2101, and supported by results in COMBI-d, COMBI-v, and BRF113928 studies
Long-Term Benefit of Nivolumab Plus Low-Dose Ipilimumab in Previously Treated Patients with MSI-H/dMMR Metastatic Colorectal Cancer
Findings of 4 years follow-up from the CheckMate 142 study
Long-Term Survival in a Significant Proportion of Patients with a 1p/19q Codeleted Anaplastic Oligodendroglioma
Final survival results in EORTC 26951 and RTOG 9402 phase III studies with addition of procarbazine, lomustine, and vincristine to radiotherapy
EMA Recommends Extension of Therapeutic Indications for Olaparib
New indication concerns the adjuvant treatment of adult patients with germline BRCA1/2 mutations who have HER2-negative, high risk early breast cancer
Age and Frailty Should Be Considered Independently When Evaluating Potential Risk for Side Effects Among Older Adults Treated with ICIs
Findings from a population-level retrospective cohort study
FDA Approves Tisagenlecleucel for Relapsed or Refractory Follicular Lymphoma
Evidence for efficacy is based on the results from the ELARA study
EMA Issues Direct Healthcare Professional Communications for Crizotinib-Related Vision Disorders in Paediatric Patients
The risk of ocular toxicity, including risk of severe visual loss and need for monitoring in paediatric patients treated with crizotinib
An Updated Overview of Estimates for Cancer Incidence and Mortality in the Latin America and the Caribbean Region
Data for 32 countries in this region reflect important underlying sociodemographic changes
Risk of Anal Cancer Significantly Lower with Treatment for Anal High-Grade Squamous Intraepithelial Lesions
Findings from a phase III ANCHOR study
Efficacy and Safety of Trastuzumab and Pertuzumab in Combination with FLOT for Perioperative Treatment of Resectable, HER2-positive Oesophagogastric Adenocarcinoma
Improved pathologic complete response and nodal negativity rates, but higher rates of diarrhoea and leukopenia observed
A Clinical Signal of Efficacy Observed with a Combination of Nivolumab and Ipilimumab Over Platinum Doublet in Fit Elderly Patients with Advanced NSCLC
Findings from the Energy-GFPC 06-2015 study