Tipifarnib Demonstrates Encouraging Efficacy in Patients with Recurrent and/or Metastatic HNSCC with HRAS Mutations
Results from the KO-TIP-001 study with farnesyltransferase inhibitor in patients with head and neck squamous cell carcinoma
Oncology News
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1616 results
FDA Grants Accelerated Approval to Melphalan Flufenamide for Relapsed or Refractory Multiple Myeloma
Evidence for efficacy is based on the results from the HORIZON study
FDA Approves Nivolumab in Combination with Chemotherapy for Metastatic Gastric Cancer and Oesophageal Adenocarcinoma
Evidence for efficacy is based on the results from the CHECKMATE-649 study
The IGCCCG Update Model Allows Improved and More Granular Individual Prognostic Assessment in Metastatic Non-Seminomatous Germ Cell Tumours
It includes age and lung metastases as additional adverse prognostic factors and uses a single cut-off of LDH at 2.5× ULN
Percentage of Cancer Patients Who Are Eligible for and Respond to Genome-Targeted Therapy Modestly Increased Over Time
A new analysis from US show that response to genome-targeted therapy increased from 2.73% in 2006 to 7.04% in 2020
FDA Grants Accelerated Approval to Sacituzumab Govitecan for Advanced Urothelial Cancer
Evidence for efficacy and safety is based on the results from the TROPHY study
FDA Approves New Dosing Regimen for Cetuximab
Approval is based on population pharmacokinetic modelling analyses
FDA Grants Regular Approval to Sacituzumab Govitecan for Advanced Triple-Negative Breast Cancer
Efficacy and safety were evaluated in the ASCENT study
EMA Recommends Granting a Marketing Authorisation for Duvelisib
PI3K inhibitor is intended for the treatment of relapsed or refractory chronic lymphocytic leukaemia and refractory follicular lymphoma
Low-Dose Aspirin Could be an Alternative to Colectomy for Preventing Colorectal Cancer in FAP
Findings from a randomised J-FAPP Study IV in patients with familial adenomatous polyposis
FDA Approves Idecabtagene Vicleucel for Multiple Myeloma
Idecabtagene vicleucel is a BCMA-directed genetically modified autologous CAR T-cell therapy
Adjuvant Nivolumab Prolongs DFS in Patients with Resected Osophageal or Gastroesophageal Junction Cancer
The CheckMate 577 study results show double longer disease-free survival with adjuvant nivolumab after neoadjuvant chemoradiotherapy and resection