Divergent HLA Allele Linked to Immunotherapy Efficacy
Researchers uncover how immune checkpoint inhibitor response relies on the evolved efficiency of HLA-mediated immunity
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Researchers uncover how immune checkpoint inhibitor response relies on the evolved efficiency of HLA-mediated immunity
Evidence for efficacy is based on the results from the BELIEVE trial
Detection and management strategies
The results of the AcSé phase II study
Findings from the ABACUS trial
Results from the phase III randomised trial
The results from KEYNOTE-048 study
Preclinical evidence and anti-tumour activity in the first dosing cohorts in patients with KRAS G12C mutated cancer
The guide is updated in October 2019
Clinical activity observed even in patients with CNS metastases and those previously treated with crizotinib
Higher proportion of serious and fatal adverse drug reactions reported among males
FDA also approved the Myriad myChoice CDx test for determination of tumour HRD status to select patients for niraparib
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