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Rheumatic immune-related adverse events resemble classical rheumatic and musculoskeletal diseases with distinct clinical and laboratory characteristics
Data from first clinical study of nivolumab in patients with pathogenic edPOLE mutated MMR-proficient tumours
The best response in sarcoma patients treated with pembrolizumab was partial response in the AcSé Pembrolizumab study
MK-4830, an antibody targeting the myeloid-specific ILT4 receptor, shows promise in advanced solid tumours
Pralsetinib had activity across all RET alterations and regardless of whether the RET mutation was somatic or germline
Sotorasib was active in patients with KRAS p.G12C mutation
Findings from the EPIC-OPC Study
During long interval studied lung cancer remained the primary tumour source in patients newly diagnosed with brain metastasis
Abemaciclib treatment induces changes in the expression of several cell cycle biomarkers
Tumour infiltrating lymphocyte levels may inform treatment decisions in women younger than 40 years with triple negative breast cancer
TERT promoter mutation may not be linked to MGMT promoter methylation-mediated sensitivity to temozolomide in IDH-wildtype glioblastoma
Nivolumab plus cabozantinib as first-line treatment for advanced clear cell renal cell carcinoma was consistently superior to sunitinib across all subgroups studied
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