NEOSTAR Results Indicate that Neoadjuvant Nivolumab Plus Ipilimumab Enhances Pathologic Responses in Operable NSCLC
Phase II randomised study met prespecified primary endpoint threshold in patients with operable non-small cell lung cancer
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Phase II randomised study met prespecified primary endpoint threshold in patients with operable non-small cell lung cancer
Abiraterone Accord is a generic of Zytiga, which has been authorised in the EU since 2011
Results of CheckMate 9ER study in patients with previously untreated advanced clear cell renal-cell carcinoma
Combination of cabozantinib and nivolumab is indicated for the first-line treatment of adult patients with advanced renal cell carcinoma
Substantial antitumour activity observed with idecabtagene vicleucel in the KarMMa study
Twice daily poziotinib dosing improved the adverse event profile; early results showed retained anti-tumour activity
Clinical benefit of FGFR inhibition is stronger in patients with an FGFR fusion or mutation compared to FGFR amplification
Endogenous and exogenous mutational processes driven by abnormal DNA editing, mutagens or age-related DNA alterations over the history of a malignant tumour provide an individual tumour signature
Prelliminary data with IL-12 mRNA administered by intratumoural injection in combination with intravenous durvalumab
Overall, more adverse events were reported with targeted therapies than with immunotherapy.
Many cancer patients with autoimmune disease are excluded from studies of immune checkpoint inhibitors due to hypothesis of the association of this treatment with immune-related adverse events
It is intended for the treatment of recurrent or advanced dMMR/MSI-H endometrial cancer that has progressed on or following prior treatment with a platinum-containing regimen
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