FDA Approves Pembrolizumab Combination for the First-Line Treatment of Cervical Cancer
Evidence for efficacy is based on the results from the KEYNOTE-826 study
Oncology News
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EMA Recommends Extension of Indications for Pembrolizumab
New indication concerns the treatment of PD-L1 positive locally recurrent unresectable or metastatic TNBC
TMB Consortium Develops a TMB Calibration Tool
Statistical calibration allows for comparison of tumour mutational burden values across various panel assays
A Third Dose of BNT162b2 is Safe and Improves Humoural Immunity Against SARS-CoV-2 in Patients with Solid Tumours
Third vaccine dose could be immunologically beneficial for patients on active chemotherapy
Merging the Histologic and Molecular Data Into an Integrated Score Significantly Improves Precision in Stratification of Meningiomas
Integrated molecular-morphologic meningiomas classification by the German Consortium on Aggressive Meningiomas
FDA Recognises OncoKB Database of Molecular Tumour Marker Information
A portion of the OncoKB is recognised as a source of valid scientific evidence for Level 2 and Level 3 biomarkers
FDA Approves Brexucabtagene Autoleucel for Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukaemia
Evidence for efficacy is based on the results from the ZUMA-3 study
Adjuvant Chemotherapy Customisation Based on ERCC1 and TS mRNA Levels Does Not Improve Efficacy in Resected NSCLC
Findings from the ITACA study in patients with completely resected, stage II-IIIA non-small cell lung cancer
EMA Recommends Granting a Marketing Authorisation for Ripretinib for the Treatment of Advanced GIST
It is indicated for the treatment of adult patients who have received prior treatment with three or more kinase inhibitors, including imatinib
Abiraterone Acetate Plus Prednisone and LHRH Analogue is Active and Safe in AR-Expressing, Castration-Resistant Salivary Gland Carcinoma
Findings from a phase II study in second-line treatment
EMA Recommends Extension of Therapeutic Indications for Nivolumab
New indication concerns the first-line treatment of adult patients with HER2-negative advanced or metastatic gastric, GEJ or oesophageal adenocarcinoma
Patients Treated With Chemotherapy and B Cell–Targeting Agents Show Impaired Serological Response to COVID-19 Vaccination
Findings from the largest study to measure anti-SARS-CoV-2 antibody levels after vaccination in patients with haematological and solid malignant tumours