Molecular Profiling with Targeted Panel Tests that Includes Fusion Detection Has a Substantial Clinical Impact for Young Patients with Solid Tumours
Findings from the GAIN/iCat2 Study in patients with extracranial solid tumours
Oncology News
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1533 results
FDA Approves Lisocabtagene Maraleucel for Second-Line Treatment of Large B-Cell Lymphoma
Evidence for efficacy is based on the results from the TRANSFORM and PILOT studies
Leveraging Extensive Real-World Data to Systematically Identify Mutations that Predict the Outcomes of Patients with Eight Common Cancer Types on Specific Therapies
Findings from a large-scale computational analysis
EMA Recommends Granting a Marketing Authorisation for Asciminib
It is a new therapeutic option for adults with Philadelphia chromosome‑positive chronic myeloid leukaemia in chronic phase, previously treated with two or more tyrosine kinase inhibitors
Pharmacokinetically Guided Dose Optimisation of Oral Targeted Therapies Reduces the Proportion of Underexposed Patients
Findings from the Dutch Pharmacology Oncology Group - Therapeutic Drug Monitoring study show that pharmacokinetically guided dose-adjustments of oral targeted therapies are feasible in clinical practice
Electronic Symptom Monitoring with PROs Improves Patient-Reported Physical Function, Symptom Control, and HRQoL
Findings from the PRO-TECT (Alliance AFT-39) cluster randomised study should be interpreted provisionally pending results of the primary outcome of overall survival
EMA Recommends Granting a Marketing Authorisation for Biosimilar Bevacizumab
Vegzelma is highly similar to the reference product Avastin, which was authorised in the EU in January 2005
A Subset of Patients with NSCLC Respond Poorly to the COVID-19 mRNA Vaccines
Very suboptimal vaccine responses generated by subset of patients with non-small cell lung cancer cannot be explained solely by older age and type of vaccine
FDA Grants Accelerated Approval to Dabrafenib in Combination with Trametinib for Unresectable or Metastatic Solid Tumours with BRAF V600E mutation
Safety and efficacy were evaluated in BRF117019, NCI-MATCH, CTMT212X2101, and supported by results in COMBI-d, COMBI-v, and BRF113928 studies
Long-Term Benefit of Nivolumab Plus Low-Dose Ipilimumab in Previously Treated Patients with MSI-H/dMMR Metastatic Colorectal Cancer
Findings of 4 years follow-up from the CheckMate 142 study
Long-Term Survival in a Significant Proportion of Patients with a 1p/19q Codeleted Anaplastic Oligodendroglioma
Final survival results in EORTC 26951 and RTOG 9402 phase III studies with addition of procarbazine, lomustine, and vincristine to radiotherapy
EMA Recommends Extension of Therapeutic Indications for Olaparib
New indication concerns the adjuvant treatment of adult patients with germline BRCA1/2 mutations who have HER2-negative, high risk early breast cancer