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The results of a phase II study of neoadjuvant pembrolizumab for patients with localised mismatch repair deficient/microsatellite instability-high solid tumours
The Clinical Trials Information System will become mandatory for all authorisation application for a clinical trial in the EU on 31 January 2023
Evidence for efficacy is based on the results from the GO29781 study
Findings from the ongoing KRYSTAL-1 phase I/II study in patients with metastatic colorectal cancer with a KRAS G12C mutation
Findings from the phase I and phase II portions of the CodeBreaK 100 study
It is the first drug to receive a labelling update under Project Renewal
New indications concern the combination treatment of metastatic non-small cell carcinoma and of advanced or unresectable hepatocellular carcinoma
New indication concerns the treatment of unresectable or metastatic HER2-low breast cancer
Different molecular subtypes of appendiceal adenocarcinomas have distinct clinical and biological behaviours that may be useful in guiding therapeutic decision
Findings from a combined analysis of SOFT-TEXT after a median follow-up of 13 years
Glofitamab induces durable complete responses in patients with relapsed or refractory diffuse large B-cell lymphoma
FDA also approved the QIAGEN therascreen KRAS RGQ PCR kit (tissue) and the Agilent Resolution ctDx FIRST Assay (plasma) as companion diagnostics
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