Imetelstat Shows Durable Transfusion Independence and Disease-Modifying Activity in Heavily Transfused Patients with Lower-Risk MDS Who Are Not Responding to Or Are Ineligible for ESA
Findings from the IMerge study
Oncology News
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1548 results
FDA Approves Nirogacestat for Desmoid Tumours
Evidence for efficacy is based on the results from the DeFi study
EMA Recommends Granting a Marketing Authorisation for Trametinib for the Treatment of Low- and High-Grade Glioma
Positive opinion was adopted for the treatment of patients aged one year and older
Sotorasib in Combination with Panitumumab Results in Longer PFS in Patients with Chemorefractory KRAS G12C-mutated mCRC
Findings from the CodeBreaK 300 study
Neoadjuvant Toripalimab Combined with Axitinib Demonstrates a Promising Pathologic Response Rate in Resectable Mucosal Melanoma
Findings from a phase II study
First Study to Demonstrate that PD1 Immune Checkpoint Blockade May Yield Clinical-Pathologic Regression in Some Patients with High-Risk Oral Precancerous Disease
Findings from a phase II non-randomised controlled study in patients with high-risk oral proliferative verrucous leukoplakia
EMA Recommends Extending Indications for Pembrolizumab to Patients with Advanced Biliary Tract Carcinoma
New indication concerns a combination with gemcitabine and cisplatin in first-line treatment
FDA Amends Indication for Pembrolizumab in the First-Line Treatment for Patients with Locally Advanced Unresectable or Metastatic HER2-positive Gastric Cancer
Updated indication restricts the use to patients whose tumours express PD-L1 CPS ≥ 1 as determined by an FDA-approved test
A Combination of Osimertinib Plus Pemetrexed and a Platinum-based Agent Significantly Improves PFS in First-Line Treatment of Patients with EGFR-mutated Advanced NSCLC
Findings from the FLAURA2 study
Efficacy of Rituximab Maintenance in Patients with Mantle Cell Lymphoma Who Are MRD-negative After Induction
Findings from the European MCL Elderly study
EMA Recommends Extension of Indications for Talazoparib
New indications concerns a combination with enzalutamide for the treatment of adult patients with mCRPC in whom chemotherapy is not clinically indicated
A Combination of Trastuzumab with Gemcitabine and Cisplatin Shows Promising Activity in Patients with Treatment-Naïve HER2-positive Biliary Tract Cancer
Findings from the TAB study