EMA Recommends Extension of Therapeutic Indications for Selpercatinib
New indication concerns the treatment of adults and adolescents with RET fusion-positive thyroid cancer that is radioactive iodine-refractory
Oncology News
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Genomic and Immunophenotypic Heterogeneity of Acquired Resistance to Immune Checkpoint Inhibitors in NSCLC
Findings from a comprehensive genomic profiling and immunophenotypic characterisation
Development of Secondary T-Cell Cancers After the Use of CAR T-Cells for the Treatment of Relapsed or Refractory Haematologic Malignancies
In few cases for which genetic sequencing has been performed to date, the CAR transgene has been detected in the malignant clone
Efficacy of Sintilimab in the Adjuvant Treatment for Patients with Resected, High-Risk Hepatocellular Carcinoma
Findings from a phase II study
FDA Approves Pembrolizumab with Chemoradiotherapy for FIGO 2014 Stage III-IVA Cervical Cancer
Evidence for efficacy is based on the results from the KEYNOTE-A18 study
No Improvement in OS with Adding Palbociclib to Letrozole for the Treatment of ER-positive, HER2-negative Advanced Breast Cancer
Findings from the final overall survival analysis of PALOMA-2 study
Adjuvant mRNA-4157 Plus Pembrolizumab Prolongs RFS versus Pembrolizumab Alone in Patients with Resected High-Risk Melanoma
Findings from KEYNOTE-942 study
Neoadjuvant Histotype-Tailored Treatment with Trabectedin Not Inferior to Standard Chemotherapy with Anthracycline Plus Ifosfamide in High-Grade Myxoid Liposarcoma
Results of the expanded cohort of a randomised study from Italian, Spanish, French, and Polish sarcoma groups
FDA Approves Belzutifan for Advanced Renal Cell Carcinoma
Evidence for efficacy is based on the results from the LITESPARK-005 study
Proof of Concept for the Safety and Immunogenicity of Lymph Node Targeting KRAS Mutation Specific Amphiphile Vaccine and Promising Signal of Clinical Activity
Findings from the AMPLIFY-201 study
EMA Recommends Granting a Marketing Authorisation for Pomalidomide Viatris
It is a generic of Imnovid, which has been authorised in the EU since 2013
The First Report from the Cancer Programme of the 100,000 Genomes Project
The 100,000 Genomes Project establishes the infrastructure and resources for linking genomic and longitudinal clinical life course data