Molecular Profiling in Routine Practice for Advanced Cancers
Limited clinical benefit achieved in the ProfiLER study
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Limited clinical benefit achieved in the ProfiLER study
Tumour-agnostic medicine is approved in Japan for adult and paediatric patients with NTRK fusion-positive advanced recurrent solid tumours
More research is also needed to identify optimal biomarkers
NeoCombi and OpACIN-neo point to a critical assessment of patterns of relapse to two neoadjuvant treatment approaches
An update on the registration-enabling ARROW study
Efficacy was investigated in patients who had disease progression on or after two or more prior lines of therapy and enrolled in the KEYNOTE-158 Cohort G or KEYNOTE-028 Cohort C1
Latest data from KEYNOTE-001 study provide the longest efficacy/safety follow-up in this setting
Long terms outcomes in BRAF V600-mutated unresectable or metastatic melanoma
Review of handling errors with depot formulations of leuprorelin medicines
Approval is based on Study GO29365 that included a cohort of patients with relapsed or refractory diffuse large B-cell lymphoma after at least one prior regimen
KEYNOTE-062 shows that front-line pembrolizumab may be promising alternative to chemotherapy
FDA also expanded the intended use for the PD-L1 IHC 22C3 pharmDx kit to include use as a companion diagnostic for selecting patients with HNSCC
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