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Clinical Practice Guidelines – Sinonasal Malignancy

Sinonasal malignancy: ESMO–EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up

Published online: 6 February 2025 - ESMO Open
Resteghini C, Baujat B, Bossi P, et al., on behalf of the ESMO Guidelines Committee

  • The CPG provides key recommendations and algorithms for managing SMs, excluding mucosal melanoma and soft tissue sarcomas.
  • The guideline covers diagnosis, staging, risk assessment, treatment and disease monitoring.
  • Technological advancements in treatment with RT are discussed with a special focus on particle therapy.
  • Surgical indications for open and transnasal endoscopic surgery are provided.
  • Neoadjuvant chemotherapy in high-grade, locally advanced SMs helps to select subjects for conservative treatments.

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