ESMO Clinical Practice Guideline interim update on the treatment of locally advanced oesophageal and oesophagogastric junction adenocarcinoma and metastatic squamous cell carcinoma
Published online: 12 February 2025 - ESMO Open
Obermannová RL & Leong T, on behalf of the ESMO Guidelines Committee
- This update provides recommendations for perioperative treatment of locally advanced oesophageal and OGJ adenocarcinoma.
- Recent phase III data have demonstrated that perioperative ChT should be the preferred approach for most patients.
- Updated recommendations are also provided for the use of immune checkpoint inhibitors in advanced squamous cell carcinoma.
- Algorithms for the management of locoregional oesophageal cancer and advanced squamous cell carcinoma are provided.
- Recommendations are based on available scientific data and the authors’ collective expert opinion.