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ESMO Clinical Practice Guideline Express Update on the management of metastatic pancreatic cancer

Published online: 9 April 2025 - ESMO Open
Conroy T & Ducreux M, on behalf of the ESMO Guidelines Committee

  • This ESMO Clinical Practice Guideline update addresses developments in the management of metastatic pancreatic cancer.
  • It has been issued following the approval of first-line nanoliposomal irinotecan (NALIRIFOX regimen).
  • Updated first- and second-line treatment recommendations are provided.
  • An updated management algorithm for metastatic pancreatic cancer is also included.

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