Fellowship type
This is a 10 session non-training post funded through The Christie NHS Foundation Trust for up to 2 years.
Position
Replacement
Available vacancies
Several positions available
Job Description
You will work with the experimental medicine consultants Dr Natalie Cook, Prof. Fiona Thistlethwaite, Dr Louise Carter, Dr Matt Krebs, and Dr Donna Graham, research nurses, Clinical Trials Coordinators, Translational Research Technician, secretarial support, as well as working alongside rotating clinical fellows and specialty trainees. The team is supported by medical and clinical oncology colleagues in all major tumour types.
You will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to be involved in the development & planning of new studies.
The Fellow will maintain a level of continuing professional development. There is the potential to present research work & you will be expected to be involved in writing papers & reviews. You will also be required to undergo an annual appraisal.
The Fellow will be expected to fully contribute to both undergraduate & postgraduate teaching, all relevant aspects of clinical governance & audit.
You will be based within ECMT, providing medical support to the consultants by primarily acting as co-investigator on Phase I clinical trials. With consultant oversight, you will be responsible for seeing new referrals, follow-ups & for managing the patient throughout all aspects of their trial experience. They will join a highly motivated & empowered workforce to increase research capacity & deliver innovative early phase research in compliance with Good Clinical Practice, Trust policy & other relevant requirements.
The remit of the ECMT is to undertake cutting edge research in developing new therapeutics & conducting translational cancer research. Phase I trials are an important first step in the drug development process & are not only designed to test the safety & tolerability of novel agents but interrogate new drug formulations, combinations, pharmacokinetics & pharmacodynamics.
Duties and responsibilities
Role: The successful candidate will be recruited as a Senior Clinical Fellow in the Experimental Cancer Medicine Team
Research: A diverse range of clinical research trials are in progress and, following training, you will be expected to participate in these studies as a co-/sub-investigator. These include Phase I trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality Phase I trials, molecular characterisation / translational studies.
You will be involved in managing all aspects of trial patients, across a diverse range of solid tumours, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments. Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 5 trial outpatient clinics per week.
You will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, the post-holder will interface with external stakeholders such as CROs and pharmaceutical sponsors.
The post-holder will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll in early phase trials.
Protocols: You will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to harness opportunities to be involved in the development and planning of new studies.
Professional Development: You will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and You will be expected to be involved in audit, writing papers and reviews. You will also be required to undergo an annual appraisal.
Teaching Commitment:
a) Undergraduate
You will be required to contribute to the undergraduate teaching of medical students on oncology topics.
b) Postgraduate
The ECMT has a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics. You will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team.
You will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.
Clinical Governance: You will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the experimental cancer medicine team.
Audit: You will play a full role in clinical audit as a member of The Christie Medical Staff Committee. The appointee will develop, supervise and deliver team audit projects.
Training Experience Required
The position is suitable for individuals ideally having completed at least CMT training but those at the end of FY2 may also be considered. A more senior role may be available for those towards the end of, or having completed, their specialist oncology training who wish to gain further experience in experimental medicine & Phase I trials, including first-in-human trials, clinical pharmacology trials & translational research.
Application deadline
12 March 2023
