Dr Fazio graduated at the University of L’Aquila, Italy, Faculty of Medicine and Surgery, in 1988, where he also specialised in Internal Medicine in 1993. He specialised in Oncology at the University of Milan in 2002.

In 2013 he gained his PhD in Digestive Oncology at the University of Rome “La Sapienza”.

Dr Fazio is currently Director of the Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumours and Director of the Programme in Digestive and Neuroendocrine Tumours at the European Institute of Oncology, in Milan, Italy, where he has been working since 1995. 

Since 2015 he is head of the IEO ENETS Centre of Excellence for GEP NETs. 

Dr Fazio is member of the European Society for Medical Oncology (ESMO).

He has been serving as ESMO Faculty Coordinator for Neuroendocrine, Endocrine and CUP for the period 2016-2019. He served as chair of the ESMO NEN Preceptorship in 2017, 2018 and he has been appointed as chair of the ESMO NEN Preceptorship and the ESMO NEN Advanced Course in 2019. 

Since 2015 he has been member of the European Neuroendocrine Tumour Society (ENETS) Advisory Board and in 2018 he was elected Advisory Board Speaker. He is member of  the  Associazione Italiana di Oncologia Medica (AIOM) and the Italian Association of Neuroendocrine Tumours (ItaNET) and since 2013 he is coordinator of the Italian (AIOM/ITANET) neuroendocrine neoplasms guidelines.

Dr Fazio is also member of the American Society of Clinical Oncology (ASCO) and the North American Neuroendocrine Tumour Society (NANETS). 

In his role at IEO he is involved in the multidisciplinary management of patients with neuroendocrine neoplasms, gastrointestinal and hepato-biliopancreatic cancers. 

His research has focused on multidisciplinary and translational clinical research in neuroendocrine neoplasms and upper gastrointestinal cancers (particularly stomach and bilio-pancreatic cancers). 

He has participated as speaker in several national and international meetings and has published around 150 publications in peer-reviewed journals.