Elizabeth (Lizzy) Smyth graduated from University College Dublin, Ireland in 2002. She commenced her oncology training in Dublin, Ireland and in 2009 she was awarded a fellowship from the Irish Society of Medical Oncology to train at Memorial Sloan-Kettering Centre, New York. Following this, she was awarded the Irish Health Service Executive Richard Steevenson Scholarship to complete her training at the Royal Marsden Hospital in London. She completed an MSc in Clinical Trials in 2011 (University of London) and was awarded an MD(Res) from the Institute of Cancer Research in 2018.

Dr. Smyth works as a consultant medical oncologist in upper GI oncology at Oxford University NHS Foundation trust with a research focus in oesophagogastric cancer. Her interests are clinical trials and translational research, and she has worked on trial design and management of national and international investigator initiated trials.

Dr. Smyth has published more than 200 peer-reviewed manuscripts in her field. She is a member of the European Society for Medical Oncology (ESMO) Upper GI Faculty, and is the Chair of the Guidelines Committee and member of the ESMO Council. She has previously served as the Chair of the ESMO OncologyPRO Working Group, Chair of the ESMO National Societies Committee and was Subject Editor for the most recent ESMO Gastric Cancer and Oesophageal Cancer Guidelines. Dr. Smyth is the current Chair of the EORTC GI Trials Group (2024-2027). In 2022, Dr. Smyth was a founding member of the UK & Ireland Oesophagogastric Cancer Group (UKIOG) and is a trustee of the UKIOG Charity. She is committed to furthering national and international collaboration in GI trials research and improving outcomes for patients with gastrointestinal cancer.