Postdoctoral postition

Institution

The Laboratory for Protein Phosphorylation & Proteomics of the KU Leuven
Campus Gasthuisberg
Herestraat 49
B-3000 Leuven
Belgium

Job

Job Title

Postdoctoral position in Protein Kinase D inhibitor drug development for cancer therapy

 

Job Description

The Laboratory for Protein Phosphorylation & Proteomics of the KU Leuven (Belgium), headed by Prof. Johan Van Lint, has a 3-year position available for a highly motivated postdoctoral scientist to further our research on the development of Protein Kinase D (PKD) inhibiting drugs. Over the years, our team discovered the involvement of these enzymes in a variety of cancer hallmarks (see our recent review paper in Oncogene, PMID 29259300). The successful candidate will use structure based approaches for investigation of PKD2 regulation and inhibition, and will exploit these for the rational development of novel PKD inhibitor drugs (e.g. allosteric ones) in collaboration with KU Leuven chemists.

Responsibilities

 

  • Initiate and develop specific research projects in the lab.
  • Work with minimal supervision using own initiative and creativity to prioritize and investigate key research questions under the guidance of the Principal Investigator.
  • Improve established protocols/techniques and implement or develop new ones.
  • Provide guidance and supervision of PhD students and other members of the lab.
  • Coordinate collaborative work within the lab and with other teams.
  • Present data at internal and external meetings.
  • Write manuscripts and assist in writing grant proposals.
  • Contribute to a cohesive and nice working atmosphere in the lab.
  • Develop academic independence.

 

Profile

 

  • You hold a PhD in Biochemistry, Biomedical Sciences, Cell Biology, Structural Biology, Molecular Biology, Pharmacology,
  • Bioengineering or equivalent related fields, with a focus on molecular mechanisms of protein regulation and/or drug design.
  • You obtained your PhD degree no longer than 3 years prior to the starting date of this position (and have no more than 3 years of postdoctoral experience). During the past 3 years, you resided no longer than 2 years in Belgium.
  • You feel comfortable with very detailed molecular protein research in the field of cellular signal transduction.
  • You are a team player with good oral and written communication skills.

 

Considered additional assets

 

  • Demonstrated skills in structural biology (e.g. protein structure determination) and/or rational drug design.
  • Demonstrated skills in protein kinase and protein phosphorylation research.
  • Skills in molecular analysis of proteins (3D structure viewing and analysis).
  • Experience with protein purification and protein analysis techniques.

 

Offer

  • You will be able to work in a KU Leuven team with 5 decades of experience in protein phosphorylation research, with excellent collaborative connections to other teams within KU Leuven, the KU Leuven Center for Drug Design & Discovery (CD3), the Leuven
  • Cancer Institute, and abroad.
  • A postdoctoral scholarship for 3 years.
  • Access to top level state-of-the-art research infrastructures.
  • A stimulating, diverse and international research environment in a world-class university (KU Leuven ranking: worldwide no. 47, Europe no. 14, Reuters innovation index no. 1).
  • Start date: as soon as possible – the position is available immediately.For more info  click here. You can also click through to find more information on the project

How to apply?

Please e-mail your full CV, including a list of your published papers/major accomplishments to Prof. Johan Van Lint, head of the Laboratory for Protein Phosphorylation & Proteomics, Department of Cellular & Molecular Medicine, KU Leuven, Belgium. Contact details Prof. dr. Johan Van Lint: tel.: +32 16 33 08 20 mail:  johan.vanlint@kuleuven.be.

Application deadline

May 20, 2018 via the  online application tool.

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at  diversiteit.HR@kuleuven.be.

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